A group of 50 states and territories in the US have launched an investigation into Google's dominance of the online advertising market.
The coalition warned that the search giant may be threatening competition and consumers.
They also raised concerns over the way Google ranks its search results and protects users' personal data.
The action adds to a mounting number of probes of big technology firms by US authorities.
On Friday, a separate group of states announced they had launched an investigation of Facebook to determine whether it had stifled competition and adequately protected consumer data.
The recent actions involve both Republicans and Democrats, a sign of growing political consensus about the need to curb the tech giants.
Texas Attorney General Ken Paxton, whose office took the lead making the announcement, said Google dominated "all aspects of advertising on the internet and searching on the Internet".
"There is nothing wrong with a business becoming the biggest game in town if it does so through free market competition," he said.
"But we have seen evidence that Google's business practices may have undermined consumer choice, stifled innovation, violated users' privacy and put Google in control of the flow and dissemination of online information."
Google accounts for about 38% of digital advertising spending in the US – at around $48bn – followed by Facebook at about 22%, according to eMarketer.
However, its share of the market has declined in recent years, as companies such as Amazon attract more spending.
Google referred questions about the latest probe to a statement it published last week, which emphasised the firm's track record of innovation.
Criticism of its business is "not new", it added.
"We have always worked constructively with regulators and we will continue to do so," it said.
'A big deal'
Historically, the US has lagged Europe and other countries when it comes to regulating the tech companies.
However, in July the US Justice Department said it would review whether practices by "leading online platforms"Read More – Source