Lacazette was struggling with a groin injury during the international break and withdrew from Frances squad just hours after replacing Anthony Martial, but the 27-year-old striker returned to Arsenal training on Wednesday.
While Unai Emery claimed that Lacazette would be available at Dean Court earlier this week, there was no place for the Frenchman in Arsenals 18-man squad.
Alexandre Lacazette (tight groin) misses out today as a precaution, Arsenals official Twitter account revealed ahead of kick-off.
Asked about Arsenals fitness concerns at his pre-match press conference on Friday, Emery replied: Today all the players trained OK. Only Danny [Welbeck] who has an injury and also Nacho Monreal now is not OK for Sunday.
Laurent Koscielny now is close with us to start maybe little by little taking minutes. Its good news.
Stephan Lichtsteiner is starting to train with us but for Sunday he is not OK. We will look tomorrow.
Henrikh Mkhitaryan, Alex Iwobi and Pierre-Emerick Aubameyang have been selected in attack and Emery has opted for a back five against Eddie Howes men.
Granit Xhaka, who starts alongside Lucas Torreira in midfield, has been chosen as the Gunners captain at Dean Court.
Mesut Ozil, meanwhile, is a notable omission in Emerys starting XI and has to settle for a place among Arsenals substitutes.
The German midfielder reacted angrily after being substituted in Arsenals 2-2 draw with Crystal Palace last month and was also replaced in the second half at Wolves.