Led by University of Bristol and International Agency for Research on Cancer, the study found women who are more “apple-shaped” are at a greater risk of the deadly disease.
It was warned these women have a higher risk compared to men with beer bellies and this is caused by a secretion of chemicals which causes inflammation which increases the chance of tumours developing.
Dr Emma Vincent of the University of Bristol said: “We found that where fat is on our body may lead to different health outcomes for men and women.
“This could inform specific prevention strategies.”
The study, published in the journal BMC Medicine, looked at 125,915 people from 45 studies on bowel cancer.
This type of cancer, which is strongly linked to obesity, affects more than 42,000 people every year, and causes more than 16,000 deaths.
The research is one of the largest genetic studies to look at men and women’s weight and bowel cancer risk.
Natasha Paton, health information manager at Cancer Research UK, added: “It’s well established that keeping a healthy weight affects many types of cancer.
“Most research linking excess weight to cancer uses BMI, but this study adds to the evidence that carrying excess fat around the waist is also important.”
Genevieve Edwards, chief executive of Bowel Cancer UK, said: “This study adds to the growing evidence that being overweight or obese and carrying a lot of weight around your waist can increase your risk of bowel cancer.
“We know that around half of all bowel cancers could be prevented by having a healthier lifestyle.
“Bowel cancer is the fourth most common cancer in the UK – every 15 minutes someone is diagnosed.”
In a study published in the US National Library of Medicine National Institutes of Health, the influence of obesity on the risk of developing colon cancer.
The study noted: “Colon cancer is the second most common cause of cancer death.
“Obesity and physical inactivity are strong independent determinants of insulin resistance and hyperinsulinemia.
“A diet high in refined sugars and low in fibre, often linked to colon cancer, also causes hyperinsulinemia.
“Obesity increases serum leptin levels.
“Leptin may also be responsible for colon cancer, but the evidence is less clear cut. Leptin was shown to increase the growth and proliferation of a colon cancer cell line.”
Other risks for developing bowel cancer can depend on many things including age, genetics and lifestyle factors.
Many studies have shown that eating lots of red and processed meat increases the risk of bowel cancer.
According to Cancer Research UK, it is estimated that around 13 out of 100 bowel cancer cases in the UK are linked to eating these meats.
Processed meat is any meat that has been treated to preserve it and/or add flavour – for example, bacon, salami, sausages, canned meat, or chicken nuggets. A portion is about two sausages or three slices of ham.
Feeling overly tired may be caused by bowel cancer, warned charity Bowel Cancer UK.
The disease has been linked with an iron deficiency, which subsequently leads to anaemia.
Anaemia symptoms include feeling very tired, and it may even make the skin appear paler than normal.
You should consider speaking to a doctor if your tiredness seems worse than normal, and lasts for at least three weeks.