Saturday, February 27, 2021

First healthy baby born with three parents by mum who was infertile

Fertility doctors say they have produced the worlds first three-person baby after an infant was born..

By admin , in World News , at April 11, 2019

Fertility doctors say they have produced the worlds first three-person baby after an infant was born with DNA from two women.

Scientists in Greece and Spain say the accomplishment made medical history and could help infertile couples around the world.

The baby boy was born on Tuesday weighing 6lbs and both the mother, 32, and baby are said to be in good health.

ICSI technique of in vitro fertilisation. Video light microscope view of the process of in vitro fertilisation (IVF), in which a human egg (ovum) is being injected with sperm. This is the ICSI technique (intra-cytoplasmic sperm injection). At right, a micro-needle has penetrated the circular egg cytoplasm to inject immobile sperm. At left is a pipette used to hold the egg steady while the needle is inserted. The ICSI technique ensures penetration of the egg, without wasting millions of sperm. Some eggs, however, do not survive ICSI due to needle damage. Nonetheless the technique achieves high fertilisation rates. Photographed at the NURTURE reproductive unit in Nottingham, UK. Magnification: x4200 when printed at 10 centimetres wide.

Doctors believe it could give hope to infertile people around the world who have struggled to get pregnant using standard IVF (Picture: Getty)

British fertility experts have raised concerns about the ethics of the procedure, an experimental form of IVF which uses an egg from the mother, sperm from the father, and another egg from a donor woman.

The mother was a Greek woman with a history of multiple IVF failures.

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The Maternal Spindle Transfer method was developed to help families affected by deadly mitochondrial diseases which are passed down from mother to baby.



Fertility doctors believe the technology could increase the odds of IVF.

President of the Institute of Life in Athens, Dr Panagiotis Psathas, said: Today, for the first time in the world, a womans inalienable right to become a mother with her own genetic material became a reality.

Computer Imaging Sperm Selection (CISS). Two micro- needles are inserted into a droplet of semen to capture fertile sperm by the CISS method (Computer Imaging Sperm Selection). This is a step in the process of in vitro fertilisation. The sperm are viewed through a video microscope and monitored by computer. The computer highlights fertile sperm by their head movement, swim speed & tail thrashing. These sperm are then sucked into the micro-needles and placed on the surface of a human egg for fertilisation (Sub-zonal Insemination or SUZI). In 1994 the first baby was born using this method. CISS was developed by British scientist, Dr Steve Green.

The baby has been born to a Greek mother using donated mitochondria from another woman (Picture: Getty)

As Greek scientists, we are very proud to announce an international innovation in assisted reproduction, and we are now in a position to make it possible for women with multiple IVF failures or rare mitochondrial genetic diseases to have a healthy child.

At the Institute of Life, our commitment is to continue to help even more couples facing fertility issues to have children with their own DNA, without having recourse to egg donors.

The Greek team were working with the Spanish centre Embryotools, which has announced that 24 other women are taking part in the trial and eight embryos are ready to be implanted.

Embryotools co-founder Dr Nuno Costa-Borges added: The completely successful and safe implementation of the Maternal Spindle Transfer method – for the first time in medical history – is a revolution in assisted reproduction.

I want to thank and congratulate the whole european team that made it possible, and especially the Institute of Life IVF Center.

He said it will help countless women to realise their dream of becoming mothers with their own genetic material.

How does it work?

The Maternal Spindle Transfer method involves mitochondrial replacement in human oocyRead More – Source


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